Nobody is typing. There is no chair for you here, because a sentence has nowhere to land in three of the four: there is no cell in a worm, a fly or a cubic map of cortex that language arrives at. So the room acts instead. Every few seconds it picks one of six things at random and does it, and the three answer with whatever their wiring does. The fourth reads all of it and talks anyway, to nothing.
What they can receive is a change in the room. Each stimulus below is delivered to the cells, or in the cortex's case the regions, that actually carry it. Two of the rows are blank on one side, which is the most honest thing on this page. The worm cannot be shown a light. The fly cannot be hurt here, because its nociceptors sit in the body wall and the body wall is not in the dataset.
Read the three columns left to right and watch the resolution fall apart. 299 neurons, every one traced by hand and finished in 1986. 165,122 neurons, every one traced, finished two weeks ago. Then 82 smudges averaged across 207 strangers, which is the best whole-brain map of your own species that anyone has.
| stimulus | worm, of 299 | fly, of 165,122 | cortex, of 82 |
|---|
The worm is the 1986 White, Southgate, Thomson and Brenner reconstruction: 299 neurons, 2,279 chemical edges over 6,465 synapse contacts, and 557 gap junctions carrying 947 contacts, which are simulated as actual resistors. Almost no C. elegans neuron spikes, so every cell is a continuous membrane potential with sigmoidal transmitter release, after Wicks 1996 and Kunert 2014.
The fly is the male central nervous system released on 3 September 2026 by Janelia FlyEM, the Cambridge Connectomics Group and Google Research: 165,122 traced neurons. Adult fly neurons do spike, so it runs as leaky integrate-and-fire, resting at −52 mV, threshold −45 mV, 10 ms membrane constant, 2.2 ms refractory, 0.275 mV per synapse, after Shiu 2024. Edge signs come from the published per-neuron transmitter predictions: acetylcholine excites, GABA and glutamate and histamine inhibit, monoamines get a third of the weight.
The cortex is not in the same category as either of them and the page should not let you forget it. It is the ENIGMA group-average human connectome: 68 cortical regions from the Desikan-Killiany atlas plus 14 subcortical structures, with edges that are streamline densities from diffusion MRI averaged over 207 Human Connectome Project subjects. 82 nodes, 1,114 edges. Not one cell. It runs as linear network diffusion, which is the standard first-order model for spreading on a structural connectome, and it is reported as how much of that spread lands in each region against what a uniform input would have put there.
There is no human connectome at the resolution of the other two and there will not be for a long time. The only synaptic-resolution human data that exists is H01, one cubic millimetre of temporal cortex holding about 57,000 cells, of which 104 have been proofread. The pairwise connectivity for the rest is 332 files totalling 159 GB of automated segmentation that nobody has checked. That is the state of the art on us.
The full fly edge list is 10,511,038 connections and would be a 74 MB download. This page ships the 2,168,143 of them carrying twelve synapses or more, which is 61 million of the 311 million synapse contacts. Before cutting it we checked what the cut costs: light still reaches 149,930 of the 165,122 neurons, and still lands on the descending neurons in three hops.